I have no way of knowing this for sure, but I'm absolutely convinced that Foster Friess -- the right-wing billionaire who's funding Rick Santorum's comic bid to repeal the 20th century -- is the person responsible for the creation of this meme. It was Friess, after all, who brought the term "back in my day" back from the dead when he looked back with nostalgia on a fairy tale time when all "gals" needed to practice effective birth control was aspirin.
“Back in my day, they used Bayer aspirin for contraceptives," the moneyed fossil told MSNBC's Andrea Mitchell. "The gals put it between their knees and it wasn’t that costly."
My only beef with the Pissed Old Guy meme is that it hasn't delved into other clever off-label uses for aspirin. I suppose there's still time.